Stem cell therapy in the Chinese market is more complicated and more confusing. Many Chinese hospitals claim to use stem cells to treat paraplegic patients, claiming to have a certain effect, and even attracting foreign patients to come to China for treatment. However, American doctors have evaluated some American patients who have received stem cell treatment in China and found that they have no effect.Some patients feel that they have improved after receiving treatment, which may be due to psychological hints or other operations not related to stem cells. Factors. In this type of treatment, stem cells from other people are directly injected into the body without inducing and differentiating the stem cells in vitro. There is a risk of rejection and carcinogenesis.
However, there are still many problems that need to be solved if these designs are to become a reality. If the stem cells used in the treatment come from others, when they are transplanted into the patient, they may cause rejection reactions and lead to failure of the operation. If the stem cells are from the patient (for example, from adult stem cells), although they will not cause rejection, if the stem cells are simply injected back into the body, the differentiation and growth of the stem cells are not controlled, and it is possible to grow tumors and cause cancer. . Even if stem cells have been induced to differentiate into the desired cell types in vitro, whether they can reach the desired site and control their growth when injected into the body are uncertain factors.
Before a therapy is applied to the clinic, animal experiments must be done first, and then human clinical trials. In 2005, researchers at the University of California, Irvine injected neural stem cells isolated and cultured from the fetal brain into paraplegic mice and found that these stem cells migrated to the injured area of ​​the mouse spine, where new neurons and oligodendrocytes were formed. Cells, paraplegic mice resumed walking. Based on this result, the US Food and Drug Administration approved it for human clinical trials in 2009. This is the first approved clinical trial of stem cell therapy in humans. In October 2010, a young man paraplegic due to a car accident became the first tester. He was injected with 2 million oligodendrocyte precursors from embryonic stem cells. But a year later, the trial team announced that the clinical trial was terminated due to funding reasons. No single stem cell treatment has been approved by the US Food and Drug Administration.
However, the stem cell treatment in China is not used in animal experiments and human clinical trials at all, and it is directly used for clinical treatment. The purpose is purely for profit. Some of these stem cell treatments are just a simple scam. For example, CCTV once revealed a stem cell beauty scam, claiming that as long as injections made of embryonic stem cells are used, they can be 10 to 15 years younger. A reporter also conducted a survey of the local beauty salon and found that many beauty salons have various stem cell cosmetic projects, and sell stem cell oral liquid, essence and other products. None of these products can actually contain stem cells, because it is much more difficult to isolate and cultivate human stem cells than to isolate and cultivate ordinary cells. At present, this is still a cutting-edge technology only for experimental research, and no institution has the ability to commercialize Mass production. And only living stem cells have an effect. Once they are made into injections and oral liquids, they become dead cells and no longer have the characteristics of stem cells. So even if these products are really made of stem cells, they have already become waste. Taking a step back and saying that even if these products do contain active stem cells, injection or oral stem cells will not play any role. Direct injection of stem cells can cause harmful body rejection and allergic reactions, and eating stem cells will even digest it. In short, these so-called stem cell preparations cannot really contain stem cells. Judging from the side effects of some consumers after using these products, their true ingredients may be some kind of hormone.
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